A mutagenetic tree hidden Markov model for longitudinal clonal HIV sequence data
نویسندگان
چکیده
منابع مشابه
A mutagenetic tree hidden Markov model for longitudinal clonal HIV sequence data.
RNA viruses provide prominent examples of measurably evolving populations. In human immunodeficiency virus (HIV) infection, the development of drug resistance is of particular interest because precise predictions of the outcome of this evolutionary process are a prerequisite for the rational design of antiretroviral treatment protocols. We present a mutagenetic tree hidden Markov model for the ...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2006
ISSN: 1465-4644,1468-4357
DOI: 10.1093/biostatistics/kxj033